个人简介

吴嘉琪，女，校聘副教授，硕士生导师。2020年于南京工业大学获得工学博士学位。研究领域为基于模式动物斑马鱼的基础或转化医学研究，主要研究方向：1）基于人源斑马鱼异种移植模型（zPDX）靶向肿瘤精准用药；2）基于斑马鱼模型，评价抗肿瘤化合物活；3）肿瘤血管新生调控机制研究；4）化合物毒性、安全性评价。发表相关论文10余篇。作为课题负责人，主持国家自然科学基金青年基金、江苏省自然科学基金青年基金、中国博士后基金面上项目，另主持多项企业委托项目。

主讲课程

免疫学

代表性成果

1. Bin XN, Gao YB, Pan M, Lian ZL, Cheng YZ, Wu JQ*, He MF*. Anti-inflammatory effects of 6S-5-methyltetrahydrofolate-calcium on RAW264.7 cells and zebrafish. Life Sci. 2023 Aug 15; 327:121839.

2. Zhang SR, Pan M, Gao YB, Fan RY, Bin XN, Qian ST, Tang CL, Ying HJ, Wu JQ*, He MF*. Efficacy and mechanism study of cordycepin against brain metastases of small cell lung cancer based on zebrafish. Phytomedicine. 2023 Jan; 109:154613.

3. Wu JQ, Fan RY, Zhai J, Li CY, Wei P, Shen LZ, He MF*, Wang P*, Huang XE*. Docetaxel and 5-FU enhanced the inhibitory effects of apatinib and ramucirumab on growth and migration of gastric cancer. Life Sci. 2022 May 1; 296:120439. doi: 10.1016/j.lfs.2022.120439. Epub 2022 Feb 27.

4. Zhai J†, Wu JQ†, Wang YH†, Fan RY, Xie GP, Wu FF, He YN, Qian ST, Tan AM, Yao XQ, He MF*, Shen LZ*. Prediction of Sensitivity and Efficacy of Clinical Chemotherapy Using Larval Zebrafish Patient-Derived Xenografts of Gastric Cancer. Front Cell Dev Biol. 2021 Jun 7; 9: 680491.

5. Wu JQ, Fan RY, Zhang SR, Li CY, Shen LZ, Wei P, He ZH, and He MF*. A systematical comparison of anti-angiogenesis and anti-cancer efficacy of ramucirumab, apatinib, regorafenib and cabozantinib in zebrafish model[J]. Life Science, 2020 Apr 15, 247: 117402.

6. Wu JQ†, Zhai J†, Li CY, Tan AM, Wei P, Shen LZ*, and He MF*. Patient-derived xenograft in zebrafish embryos: a new platform for translational research in gastric cancer[J]. Journal of Experimental & Clinical Cancer Research, 2017, 36(1): 160.

联系方式

邮 箱：jiaqi_wu@njtech.edu.cn

办公地点:尚德楼B1-605