个人简介:
刘嘉唯,南京工业大学校聘副教授,研究方向为废塑料生物解聚循环,主要涉及塑料降解微生物高通量筛选、微生物降解机制解析和关键解聚酶元件挖掘与改造等方面的研究。主持国家自然科学基金青年项目、国家重点研发计划子课题1项、国家博士后基金面上项目和江苏省卓越博士后计划。近年来以第一或通讯作者在Appl. Environ. Microbiol.、Biotechnol. Adv.、J. Hazard. Mater.等发表高水平SCI论文9篇,申请中国发明专利10余项。
代表性成果:
主持项目:
1. 国家自然科学基金青年项目:22408168,脂肪酶CpEst6的底物杂泛性催化机制解析及聚氨酯塑料解聚应用,2025/01-2027/12,30万元,在研,主持。
2. 中国博士后第74批面上:2023M741663,聚氨酯塑料解聚酶CpEst6多功能催化活性的分子机制研究,2023/01-2024/12,8万,结题,主持。
3. 国家重点研发计划“循环经济关键技术与装备”专项子课题:2023YFC3905000,规模化 PET 酶法解聚体系的构建与过程强化—MHET膜分离技术开发,2023/12-2027/11,27万,在研,课题负责人。
4. 江苏省卓越博士后计划:2023ZB220,C-X骨架塑料解聚酶CpEst6多功能催化活性的分子机制研究,2023/06-2025/06,30万,结题,主持。
发表文章:
1. Jiawei Liu et al. Biodegradation of polyester polyurethane by Cladosporium sp. P7: Evaluating its degradation capacity and metabolic pathways. Journal of Hazardous Materials, 2023, 448, 130776.
2. Jiawei Liu et al. Microbial degradation and upcycling of polyurethanes: progress, challenges and prospects. Biotechnology Advances, 2021, 48, 107730.
3. Jiawei Liu et al. Identification and characterization of a fungal cutinase-like enzyme CpCut1 from Cladosporium sp. P7 for polyurethane degradation. Applied and Environmental Microbiology, 2024,90(4), e01477-23.
4. Anming Xu#1, Jiawei Liu#1 et al. Application of a novel fluorogenic polyurethane analogue probe in polyester‐degrading microorganisms screening by microfluidic droplet. Microbial Biotechnology, 2023, 16(2), 474-480.
5. Jiawei Liu et al. Biodegradation of polyether-polyurethane foam in yellow mealworms (Tenebrio molitor) and effects on the gut microbiome. Chemosphere. 2022, 304,135263.
6. Jiawei Liu*, Anming Xu* et al. Screening of polyurethane-degrading microbes using a quenching fluorescence probe by microfluidic dropletsorting. Chemosphere. 2024,364,143060.
7. Jiawei Liu*, Weiliang Dong* et al. Depolymerization of the polyester–polyurethane by amidase GatA250 and enhancing the production of 4,4′‐methylenedianiline with cutinase LCC. Biotechnology Journal, 2024,19(4), 2300723.
8. Jiawei Liu et al. Biodegradation of diethyl terephthalate (DET) and polyethylene terephthalate (PET) by a novel identified degrader Delftia sp. WL-3 and its proposed metabolic pathway. Letters In Applied Microbiology, 2018, 67, 254-261.