个人简介

胡玉静，生物与制药工程学院副教授，硕士生导师。博士毕业于浙江大学，期间于英国女王大学交流学习。主要研究方向：（1）氧化还原酶催化转化及其蛋白质工程；（2）连续流中多酶催化转化合成高价值产品。以第一作者或通讯作者身份（含共同）在Angewandte Chemie International Edition、Chemical Engineering Journal、ACS Macro Letters、Advanced Synthesis & Catalysis、Chemical Communications等刊物发表多篇论文，授权中国发明专利8项。主持国家自然科学基金青年基金等数项省部级及国家级项目，以及企业委托项目3项，并获批中国石化2023（首届）“种子计划”课题。

主讲课程

本科生课程：《酶工程》

研究生课程：《绿色催化》

获奖

2024年，指导研究生获国家奖学金2项

2024年，指导研究生获江苏省研究生科研创新项目1项

2024年，荣获南京工业大学第十三届青年教师授课竞赛二等奖

2022年，指导本科生获校级优秀毕业论文1项

本课题组拟招收有志于酶催化方向的研究生数名，欢迎联系！

代表性论文(10篇）

(1) Yujing Hu, et al. Sequence Similarity Network Guided Discovery of a Dehydrogenase for Asymmetric Carbonyl Dehydrogenation, Angewandte Chemie International Edition, 2025, e202501425. （顶刊，IF=16.6）

(2) Yujing Hu*, et al. Four-Step Continuous-Flow Biosynthesis of a Chiral Precursor for Angiotensin-Converting Enzyme Inhibitors, Chemical Engineering Journal, 2025, 53, 158331.（SCI一区，IF=13.4）

(3) Yujing Hu*, et al. Ene-Reductase-Catalyzed Aromatization of Simple Cyclohexanones to Phenols, Angewandte Chemie International Edition, 2024, 63, e202408359. （顶刊，IF=16.6）

(4) Yujing Hu, et al. Enantiocomplementary Synthesis of Tetrahydrofurans by Engineered Halohydrin Dehalogenases, Advanced Synthesis & Catalysis, 2024, 366.

(5) Yujing Hu*, et al. A Photo-Enzymatic Cascade to Access Dihydrocoumarins from Incompatibility to Compatibility, Molecular Catalysis, 2024, 554, 113852.

(6) Yujing Hu, et al. Biocatalysts Used for Multi-Step Reactions in Continuous Flow, Chemical Engineering Journal, 2022, 437, 135400.

(7) Yujing Hu, et al. The Mutagenesis of a Single Site for Enhancing or Reversing the Enantio- or Regiopreference of Cyclohexanone Monooxygenases, Chemical Communications, 2020, 56(65), 9356-9359.

(8) Yujing Hu, et al. Dual-Enzyme-Catalyzed Synthesis of Enantiocomplementary Polyesters, ACS Macro Letters, 2019, 8(11), 1432-1436.

(9) Yujing Hu, et al. ‘‘Top’’ or ‘‘Bottom’’ Switches of a Cyclohexanone Monooxygenase Controlling the Enantioselectivity of the Sandwiched Substrate, Chemical Communications, 2019, 55(15), 2198-2201.

(10) Yujing Hu, et al. Customizing the Enantioselectivity of a Cyclohexanone Monooxygenase by A Strategy Combining “Size-Probes” With in Silico Study, ChemCatChem, 2019, 11(20), 5085-5092.

联系方式

邮    箱   yjhu@njtech.edu.cn

办公地点   尚德楼A1-406-1