个人简介

章文明，1988年9月生，教授，博士生导师，江苏省中德废弃碳资源生物炼制国际联合实验室副主任。2015年获南京师范大学博士学位，随后进入南京工业大学从事教学科研工作，开展一碳原料的高效生物转化、功能酵母细胞工厂的构建与调控等研究。担任3 Biotech副主编，Front Bioeng Biotech客座副主编和编委，Green Carbon、BioDesign Research青年编委，《生物学杂志》编委；中国生物工程学会一碳生物技术专委会委员、中国化工学会生物化工青年委员会委员、中国生物工程学会青年工作委员会委员、江苏省生物资源研究会监事等。

主持国家自然科学基金（3项）、国家重点研发计划子课题等纵向项目10余项，主持企业合作项目6项。以第一或通讯作者在国际知名期刊Sci Adv、Nat Commun、Met Eng、Trends Biotechnol等发表SCI论文60余篇；以第一发明人申请发明专利26件，已授权10件。主持课程思政示范项目、教育教学改革课题等4项，发表教改论文4篇；参编“十四五”普通高等教育本科系列教材及中英文学术专著8部。指导学生获iGEM（国际基因工程机器大赛）金奖、全国大学生生命科学竞赛一等奖等奖励10余项。

主讲课程

本科生：《发酵工程》、《生物工艺学》、《生物资源学导论》、《生工类专业写作》

研究生：《生物炼制技术》、《学科科技英语写作》

代表性成果

荣誉奖励

l 全球前2%顶尖科学家榜单（2024、2025）

l 中国科协“青年人才托举工程”（2021）

l 江苏省“青蓝工程”优秀青年骨干教师（2022）

l 山东省重点扶持区域引进急需紧缺人才（2024）

l 江苏省农学会青年科技奖（排名1/1，2023）

l 中国商业联合会科技进步一等奖（排名2/8，2024）

l 江苏省科学技术奖三等奖（排名3/7，2023）

l 江苏省能源研究会科学技术进步一等奖（排名3/10，2023）

l 江苏省农学会技术创新二等奖（排名2/11，2023）

l 南京工业大学青年才俊拓原工程、科学研究突出贡献奖、优秀共产党员

代表性论文

1. Wenming Zhang* et al. Evolutionary engineering of Saccharomyces cerevisiae: Crafting a synthetic methylotroph via self-reprogramming. Science Advances, 2024, 10, eadq3484.

2. Wenming Zhang* et al. Inorganic-bacterial biohybrids for efficient solar-driven nitrogen fixation. Nature Communications, 2025, 16, 5690.

3. Wenming Zhang* et al. Sustainable production through spatial niche partitioning in engineered light-driven microbial community. Metabolic Engineering, 2025, 92, 90–101.

4. Wenming Zhang* et al. Bioconversion of C1 feedstocks for chemical production using Pichia pastoris. Trends in Biotechnology, 2023, 41 (8)：1066-1079.

5. Wenming Zhang* et al. Thermophiles: potential chassis for lignocellulosic biorefinery. Trends in Biotechnology, 2022, 40:6.

6. Wenming Zhang* et al. From formate oxidation to CO₂ reduction: The role of formate dehydrogenase in sustainable carbon utilization. Biotechnology Advances, 2025, 82, 108600.

7. Wenming Zhang*, et al. Advances in the synthesis of three typical tetraterpenoids including β-carotene, lycopene and astaxanthin. Biotechnology Advances. 2022; 61, 108033.

8. Wenming Zhang* et al. Design and optimization of artificial light-driven microbial consortia for the sustainable growth and biosynthesis of 2-phenylethanol. Chemical Engineering Journal, 2023, 466: 143050.

9. Wenming Zhang*, et al. Improving methanol assimilation in Yarrowia lipolytica via systematic metabolic engineering combined with compartmentalization. Green Chemistry, 2023, 25, 183–195.

10. Wenming Zhang*, et al. Spatial niche construction for consortium-based consolidated bioprocessing system. Green Chemistry, 2022, 24, 7941.

11. Wenming Zhang*, et al. Microbial astaxanthin synthesis by komagataella phaffii through metabolic and fermentation engineering. Journal of Agricultural and Food Chemistry. 2025, 73, 1952-1964.

12. Wenming Zhang*, et al. High astaxanthin production by Xanthophyllomyces dendrorhous strain DW6 from cane molasses using two-stage pH strategies. Green Chemistry, 2024, 26, 4582–4592.

13. Wenming Zhang*, et al. Transcriptomic analysis reveals the potential mechanisms for improving carotenoid production in Rhodosporidium toruloides Z11under light stress. Journal of Agricultural and Food Chemistry, 2024, 72: 3793−3799

14. Wenming Zhang*, et al. Breeding of a Mesophilic Xanthophyllomyces dendrorhous Mutant for Industrial Astaxanthin Production and Mechanism Analysis on the Temperature Tolerance. ACS Sustainable Chemistry and Engineering, 2025, 13, 11756−11769.

15. Wenming Zhang*, et al. Formaldehyde: An Essential Intermediate for C1 Metabolism and Bioconversion. ACS Synthetic Biology. 2024, 13, 3507−3522.

16. Wenming Zhang*, et al. Increased lipid production in Yarrowia lipolytica from acetate through metabolic engineering and cosubstrate fermentation. ACS Synthetic Biology, 2021, 10: 3129-3138.

17. Wenming Zhang*, et al. Metabolic Engineering of Yarrowia lipolytica for Efficient Production of Terpenoids. Industrial & Engineering Chemistry Research. 2024, 63, 14469−14479.

18. Wenming Zhang*, et al. Metabolic engineering of Pichia pastoris for malic acid production from methanol. Biotechnology and Bioengineering, 2021, 118: 357–371.

19. 章文明*，等. 一碳资源在酵母中的利用与转化. 化工进展, 2023, 42(1): 30-39.

20. 章文明*，等. 甲醇生物转化合成化学品的研究进展. 生物工程学报, 2023, 39(6): 2430-2448.