主讲课程

《分子生物学》、《系统生物学与合成生物技术》

个人简介

2015年于天津大学获得博士学位，同年加入南京工业大学生物与制药工程学院。主要从事生物催化工程和合成生物学领域研究工作：（1）碳一原料（甲醇、CO₂）的生物转化；（2）二元胺、多元醇生产菌株的代谢工程改造和调控；（3）多酶催化合成氨基酸衍生物、含能材料、健康化学品等。荣获“333高层次人才培养工程第三层次”、“江苏省低碳技术学会拔尖青年科学家”、“南太湖精英计划创新领军人才”等荣誉称号。

代表性成果

荣誉获奖（含指导学生获奖）：

2019年，入选湖州市“南太湖精英计划”创新领军人才

2019年，荣获南京工业大学保密工作先进个人

2020年，入选江苏省低碳技术学会“拔尖青年科学家”

2020年，荣获南京工业大学第十一届青年教师授课竞赛二等奖

2020年，指导本科生获大学生创新创业大赛项目国家级立项

2021年，指导本科生获大学生创新创业大赛项目国家级立项

2021年，指导研究生获江苏省研究生科研创新项目1项

2021年，指导研究生“科创江苏”创新创业大赛一等奖

2022年，指导研究生获中国“互联网+”大学生创新创业大赛省二等奖

2022年，入选江苏省第六期“333工程”第三层次培养对象

代表性论文：

1. Xin Wang*. Rewiring (p)ppGpp metabolism for high-yield anaerobic methanol and CO₂ conversion in Butyribacterium methylotrophicum. Chemical Engineering Journal, 2026.

2. Xin Wang*. De novo biosynthesis of putrescine from glucose using engineered Escherichia coli in a two-step process.  Synthetic and Systems Biotechnology, 2026.

3. Xin Wang*. De Novo Biosynthesis of 1,5-Pentanediol by Metabolically Engineered Escherichia coli. Biotechnology and Bioengineering.

4. Xin Wang*. Metabolic engineering of Escherichia coli for production of cadaverine from lignocellulose.Journal of Agricultural and Food Chemistry, 2025.

5. Xin Wang*. Enzyme and cofactor engineering to increase D-xylonate dehydratase activity for improved D-1,2,4-butanetriol production from D-xylose. Synthetic and Systems Biotechnology, 2025.

6. Xin Wang*.Efficient production of 1,6-hexanediol from adipic acid by engineering ofcarboxylate reductase coupled with genetically modified Escherichia coli. Chemical Engineering Journal., 2025.

7. Xin Wang. Enhancing the co-utilization of methanol and CO2 into 1-butanol by equipping synergistic reductive glycine pathway in Butyribacterium methylotrophicum. Bioresource Technology, 2025.  

8. Xin Wang*. Engineering yeasts to Co-utilize methanol or formate coupled with CO₂ fixation. Metabolic Engineering, 2024.

9. Xin Wang*. Establishing an Artificial Pathway for the Biosynthesis of Octopamine and Synephrine". ACS Synthetic Biology, 2024.

10. Xin Wang*. An integrated cofactor and co-substrate recycling pathway for the biosynthesis of 1,5-pentanediol. Microbial Cell Factories, 2024.

11. Xin Wang*. Engineering RuBisCO-based shunt for improved cadaverine production in Escherichia coli. Bioresource Technology, 2024.

12. Xin Wang*. Advance of tolerance engineering on microbes for industrial production". Synthetic and Systems Biotechnology, 2023.

13. Xin Wang*. Recent advances in engineering heterotrophic microorganisms for reinforcing CO₂ fixation based on Calvin-Benson-Bassham cycle. ACS Sustainable Chemistry & Engineering, 2023.

14. Xin Wang*. Increasing lysine level improved methanol assimilation toward butyric acid production in Butyribacterium methylotrophicum". Biotechnology for Biofuels and Bioproducts, 2023.

15. Xin Wang*. A novel co-production of cadaverine and succinic acid based on a thermal switch system in recombinant Escherichia coli. Microbial cell factories, 2022.